The Daria Annotation File:
My Night at Daria's

The title is a reference to "Ma nuit chez Maud" or "My Night at Maud's" (or "My Night with Maud"). It's a 1969 film in which a devout Catholic falls in love with a girl he sees at mass, comepletely different from himself; however, a friend introduces him to a woman named Maud and they hit it off philisophically, so much that he stays the night in discussion.

Daria is reading "Macroeconomics". Although there are several textbooks by that title, the most famous is the one by Paul Samuelson, originally published in 1948.
Tom is reading "Critique of Pure Reasoning" by Immanuel Kant. The correct title should be "Critique of Pure Reason".

The name of the sushi bar is Tokyo Toby's

Tom and Daria wake up at 4:07 a.m. This is probably a reference to the song "Wake up Little Susie" by the Everly Brothers

"Wake up, little Susie, wake up
Wake up, little Susie, wake up
We’ve both been sound asleep,
Wake up, little Susie, and weep
The movie’s over, it’s four o’clock,
And we’re in trouble deep
Wake up little Susie
Wake up little Susie, well"

Helen's first time was a fling with a stunt-car driver.

The parasite Jake gets seems to be the Anisakis simplex, which can be picked up from bad sushi.

Tom mentions Route 6, but that doesn't narrow things down too much, as Route 6 runs from Rhode Island and Massachusetts to California

Sick, Sad World (the site) was created by Wraith